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diagnosis differential management algorithm liver hematology nephrology rhabdomyolysis thrombosis transaminitis acidosis arterial cardiology classification dili druginduced elevation embolism endocarditis epilepsy
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... CMV), Alcoholic cirrhosis ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... #hepatology #LFTs
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... • NAFLD • Cirrhosis ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... Differential #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
, Compartment syndrome ... decreased renal renal ischemia ... Treatment: 1 ... Management #Summary #causes ... #treatment
Causes of Pediatric Seizures - Differential Diagnosis Algorithm Infantile: • Benign Focal Epilepsy of Infancy • West
Causes of Pediatric ... Structural: • Head Injury ... • Transient Ischemic ... Diagnosis #Algorithm #Causes ... #Peds #Pediatrics
Portal Vein Thrombosis (PVT) Treatment Algorithm - If concern for ischemic: anti-coag+multidisciplinary care - W/o cirrhosis+recent
If concern for ischemic ... multidisciplinary care - W/o cirrhosis ... anti-thrombotic tx - Cirrhosis ... : case-by-cased ... management #Algorithm #hepatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... - Compartment syndrome ... perfusion → renal ischemia ... Treatment: ... Diagnosis #Management #causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... non-essential drug/HDS treatments ... for alternative causes ... disease, Hepatic ischaemia ... Diagnosis #Algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... AKI, acute limb ischemia ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
, - regional ischemia ... liver or renal injury ... - regional ischemia ... - Mesenteric ischemia ... - Compartment syndrome
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