22 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Liver Disease: Primary ... Biliary Cirrhosis ... vs Primary Sclerosing ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
or AST > ALP): ... Drugs, Viral, Ischemia ... Ducts - PBC ... Congenital, Others, Cirrhosis ... Algorithm #diagnosis #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Elevated ALP 2. ... #PBC #Primary ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... Pathophysiology ... Signs and Symptoms ... obstruction • ALP ... diagnosis #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Algorithm Severe ALT ... Drugs/Toxins • Ischemia ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... relative with PBC ... #Cirrhosis #Pathophysiology ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Most common symptoms ... disease - Bone symptoms ... - Drugs - Primary ... biliary Cholangitis (PBC ... Diagnosis #Algorithm #hepatology
A cirrhosis tweetorial all about the platelet

Aims:
- Identify cirrhosis based on blood tests- 
- Understand why
A cirrhosis tweetorial ... all about the platelet ... Aims: - Identify cirrhosis ... #CBC #Tweetorial ... #Hepatology #Pathophysiology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... This leads to RBC ... organs leading to ischemia ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... AKI, acute limb ischemia ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology