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differential management causes lfts syndrome transaminitis treatment acidosis algorithm behcet bells classification coronavirus covid19 dehydrogenase dili disease druginduced elevated elevation
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... > 20x normal - Acute ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... #Injury #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... injury - Viral ... #Differential #Hepatology ... #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... Hepatopathy • Acute ... injury) • Ischemic ... #Differential #Diagnosis ... #hepatology #transaminitis
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
of COVID-19 • Neurologic ... kidney injury, ... shock, Myocardial ischemia ... Extrapulmonary #Diagnosis ... #Signs #Symptoms
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
RBCs, muscle, liver ... hepatitis • Ischemic ... distinguishes ischemic ... • Demand ischemia ... associated with any symptoms
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
, - regional ischemia ... or renal injury ... - regional ischemia ... - Mesenteric ischemia ... Injury: • Reduced
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
GrepMed Handbook Acute ... ophthalmoplegia), systemic signs ... , facial nerve ischemia ... Imaging (if atypical symptoms ... prevent corneal injury
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... : • Triad of symptoms ... urine • Other symptoms ... perfusion → renal ischemia ... Isotonic fluid/Lactated
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... limb ischemia, ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
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