26 results
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
of disease and complications ... deformed shape, HbS ... organs leading to ischemia ... , necrosis and pain ... #Hematology #Sequelae
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
of Bone/Joint Pain ... Vaso-occlusive pain ... • Mechanism: ischemic ... other orthopedic complications ... diagnosis #causes #hematology
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
sludge), Mirizzi's syndrome ... Parasitic infection, Ischaemic ... differential #diagnosis #hepatology ... #gastroenterology
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel Syndrome ... (IBS) - Management ... and Hepatology ... Irritable #Bowel #Syndrome ... #Management #gastroenterology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... and Management ... Recurrent abdominal pain ... and Hepatology ... #gastroenterology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
• Budd-Chiari syndrome ... Irritable bowel syndrome ... Chronic mesenteric ischemia ... • Mesenteric ischemia ... Differential #Diagnosis #gastroenterology
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Necrosis Etiology: - Ischemia ... Stevens-Johnson syndrome ... retrosternal chest pain ... Necrosis #diagnosis #management ... #gastroenterology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
Irritable Bowel Syndrome ... Recurrent abdominal pain ... and Hepatology ... Irritable #Bowel #Syndrome ... Diagnosis #workup #gastroenterology
Compartment Syndrome Pearls
A vicious cycle of increased pressure within a facial compartment leading to compression of
Compartment Syndrome ... Tissue hypoxia → Ischemia ... Ischemic injury ... after the onset of ischemia ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... AKI, acute limb ischemia ... TLS #diagnosis #management ... #hematology