31 results
diagnosis differential liver rheumatology causes lfts transaminitis algorithm injury leukemia acute aih ascites autoimmune cirrhosis cll gastroenterology lymphocytic vasculitis aclf
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... 5-10x normal - Chronic ... AST:ALT = 1 - Ischemia ... , Ischemic Necrosis ... Liver #Injury #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury - Ichemic ... hepatitis - Acute ... - Autoimmune hepatitis ... - Wilson disease ... #Differential #Hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Cirrhosis • Chronic ... Viral Hepatitis ... • Acute Viral Hepatitis ... liver injury) • Ischemic ... Differential #Diagnosis #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... 15 percent) - Hepatitis ... heart failure (chronic ... (Budd-Chiari syndrome ... #Differential #Hepatology
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 Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
liver disease ( ... cirrhosis or chronic ... hepatitis) - 80% ... Fitz-Hugh-Curtis syndrome ... Differential #Diagnosis #hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Metabolic: Wilson Disease ... • Autoimmune hepatitis ... See Updated Schema ... Transaminases #hepatitis ... Diagnosis #causes #hepatology
Causes of Biliary Dilatation - Differential Diagnosis • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy •
cyst, Caroli's disease ... sludge), Mirizzi's syndrome ... Inflammatory: Chronic ... Parasitic infection, Ischaemic ... differential #diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... underlying liver disease ... (DILI) Viral Hepatitis ... #ACLF #Acute #Chronic ... Failure #Cirrhosis #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... • Cholestatic disease ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Alcohol-related liver disease ... , Hepatic ischaemia ... e.g. ascites), Chronic ... hepatitis fibrosis ... Diagnosis #Algorithm #hepatology
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