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diagnosis causes management brain cardiology concurrent betadglucan biomarkers cd4 comparison evaluation hemoptysis hiv hivaids ia invasive mycoses treatment workup
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Most invasive infections ... , Advanced HIV/AIDS ... Rhinosinusitis, CNS infection ... , Disseminated infection ... systemic vori Infectious
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... spp, Atypical infection ... Microsporidum Non-infectious ... bronchoscopy Infectious ... #Infections #HIVAIDS
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... surfaces - Infections ... BAL GM does not differentiate ... Clav (may be + as long ... setting of GVHD) ID
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
phenomena from endocarditis ... ) • Fungi: Aspergillus ... #Infections #Concurrent ... #Differential # ... Diagnosis #causes #infectiousdiseases
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
phenomena from endocarditis ... ) • Fungi: Aspergillus ... #Infections #Concurrent ... #Differential # ... Diagnosis #causes #infectiousdiseases
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
Parenchyma: • Infection ... Necrotizing PNA, Abscess ... Ebola, Dengue), Fungal ... regurgitation, Tricuspid endocarditis ... #Diagnosis #pulmonary
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Infectious: • Pre-existing ... devices (CIED) Non-Infectious ... verrucous) • Lung ... Cerebral > Splenic, pulmonary ... infarction • Infectious
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Infectious: • Pre-existing ... devices (CIED) Non-Infectious ... , verrucous) - Lung ... Cerebral > Splenic, Pulmonary ... infarction • Infectious
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pseudomonas FUNGAL ... since cART) Aspergillus ... #Infections #HIV ... #AIDS #pulmonary
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
yeast • At risk: AIDS ... ASPERGILLOSIS • Aspergillus ... Sinusitis • Brain abscess ... arthritis, and endocarditis ... ) #Mycoses #InfectiousDiseases
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