18 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... (DIC, ascites, jaundice ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... iMedEducation #AFLP
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pruritus, Mild jaundice ... of Pregnancy (AFLP ... hepatology #obstetrics #hepatitis ... #comparison #differential ... diagnosis #icp #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... CA, small cell lung ... Chronic viral hepatitis ... #injury #hepatitis ... #differential #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Check Acute viral hepatitis ... Check Acute viral hepatitis ... Chronic viral hepatitis ... chemistry #diagnosis #differential
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
Important findings: jaundice ... different) PMHx: - Focus ... biopsy Meds: ... - Outpatient meds ... prior hepatotoxic meds
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... • Alcoholic hepatitis ... #LiverEnzymes #Differential
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
onset RUQ pain, jaundice ... progressing to acute liver ... Liver transplant ... Hepatobiliary #hepatology #hepatitis ... #differential #
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminitis - Differential ... CA, small cell lung ... Trauma: Shock liver ... • Autoimmune hepatitis ... #Differential #
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Regions - Frequent Differential ... - HIV, herpes, hepatitis ... B, hepatitis C ... plague, anthrax • Jaundice ... Returning #Traveler #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
hyperpigmentation • Jaundice ... obstruction • ALP ... or higher • Liver ... bile ducts Differential ... Diagnosis: • Viral hepatitis