14 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Differential Diagnosis ... Reactive: • Anemia ... /blood loss (Fe ... Diagnosis #causes ... #Platelets #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... #Platelets #Differential ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... changes), high MCV anemia ... Diagnosis #Causes ... #Workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... with or without platelet ... Schistocytes, thrombocytopenia ... #Anemia #Differential ... #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Platelet count ... of Peripheral blood ... WBC count and differential ... #Workup #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology ... #nonpalpable #dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Most common cytopenia ... differential • ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
(FNHTR): Most common ... Causes purpura & ... severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
(FNHTR): Most common ... Causes purpura & ... severe thrombocytopenia ... #Transfusions #diagnosis ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
infections/fevers • Thrombocytopenia ... and petechiae Causes ... result from low blood ... #oncology #hematology ... #diagnosis #management