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intravascular algorithm aplastic classification dic disorders disseminated extravascular hemolysis hemolytic hodgkins lymphoma mds myelodysplasia nonpalpable petechiae petechial physicalexam platelet rash
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... OF PALPABLE PURPURA ... Diagnosis #hematology ... #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Diagnosis and Workup ... changes), high MCV anemia ... Diagnosis #Causes ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Palpable variants ... - Platelet rich ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
hemostasis: - Thrombocytopenia ... - Abnormal platelet ... deficiency Work ... Complete blood count coagulation ... #Causes #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... count (thrombocytopenia ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... #differential # ... diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... result in severe anemia ... WBC count and differential ... #Workup #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
infections/fevers • Thrombocytopenia ... and petechiae Causes ... • Hypocellular myelodysplastic ... #oncology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... - Low Hb and platelets ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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