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hepatology diagnosis differential hepatitis aflp algorithm management obstetrics pregnancy ah aih alcoholic alkphos astalt autoimmune bile bileacids biliary bilirubun biochemistry
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Bilirubin Metabolism ... • Conjugated ... Bilirubin • Unconjugated ... #Metabolism #Pathophysiology ... #hepatology #Liver
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
Biochemistry and Metabolism ... Conjugation → Conjugated ... , and conjugated ... #Biochemistry #Metabolism ... #pathophysiology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Metabolism AST ... metabolism: • ... MRP2 transports conjugated ... Tests #Laboratory #Metabolism ... #Hepatology #Pathophysiology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
of hemolysis or liver ... breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... • Increase in conjugated
Jaundice - Pathophysiology and Causes - Amy Chung, MD, MSc @AmyChung #Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... Amy Chung, MD, MSc ... @AmyChung #Jaundice ... #Pathophysiology ... #Differential #Unconjugated
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... acid metabolism ... acid metabolism ... (DIC, ascites, jaundice
Bilirubin metabolism and pathophysiology of jaundice #Bilirubin #metabolism #pathophysiology #jaundice #hepatology
Bilirubin metabolism ... and pathophysiology ... of jaundice # ... Bilirubin #metabolism ... #pathophysiology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... fold elevation, Bilirubin ... fold elevation, Bilirubin ... hemorrhage Acute Fatty ... Hepatic imaging: Fatty
Lipoprotein Metabolism Enterocytes release absorbed lipids the form of triglyceride-rich chylomicrons. These are acted upon by endothelial
Lipoprotein Metabolism ... cells producing fatty ... supply tissues with fatty ... #Cholesterol #Metabolism ... #Pathophysiology
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
) • Onset of jaundice ... • Serum total bilirubin ... within 7 days) or metabolic ... liver disease ( ... Possible drug-induced liver
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