43 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... (DIC, ascites, jaundice ... Diagnosis: Viral Hepatitis ... Liver #Pregnancy #hepatology
An Approach to Jaundice - Differential Diagnosis

- Increased Production (Prehepatic)
- Decreased Clearance (Intrahepatic + Posthepatic)

Dr. Eric
An Approach to Jaundice ... DrEricStrong #Jaundice ... Differential #Table #Causes ... Posthepatic #Diagnosis #Hepatology
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
Hepatitis B Virus ... B - Chronic hepatitis ... (about 10% of cases ... ) - Acute hepatitis ... diagnosis #laboratory #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Injury - Ichemic hepatitis ... - Autoimmune hepatitis ... Severe #Acute #Causes ... #Differential #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Pregnancy - AFLP ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pruritus, Mild jaundice ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... diagnosis #icp #HELLP #AFLP
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
diagnosis of Alcoholic Hepatitis ... ) • Onset of jaundice ... before the onset of jaundice ... Possible ischemic hepatitis ... #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
of Autoimmune Hepatitis ... - Onset of jaundice ... before the onset of jaundice ... Possible ischemic hepatitis ... #Diagnosis #Hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Infectious • Hepatitis ... • Alcoholic Hepatitis ... • Drug Induced Hepatitis ... Diagnosis #Algorithm #Causes ... #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
(Alk phos/ULN ALP ... Check Acute viral hepatitis ... Check Acute viral hepatitis ... Chronic viral hepatitis ... #differential #Hepatology