11 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
features in most cases ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical ... #Smear
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory ... arrow) Peripheral smear ... hemolytic #anemia #Hematology ... #Pathology #Smear
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... DIC, TTP, HUS) ... #Analysis #hematology ... #microscopy #interpretation ... #clinical #anemia
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... #neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
In this case, the ... Leukoerythroblastosis #Hematology ... #Pathology #Smear ... #Microscopy #Clinical
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... venipuncture sites Laboratory ... • Peripheral smear ... Treat primary cause ... treatment #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... : Blast crises ... • Peripheral smear ... Fibrinolysis & DIC ... #Leukemia #Hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... Discontinuation of causal ... • Laboratory ... comparison #table #rheumatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... rapidly develops (DIC ... , ascites, jaundice ... , ↑Tbili/Dbili/AP ... Liver #Pregnancy #hepatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... skin necrosis • DIC ... #hematology