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diagnosis management disease oncology anemia differential hodgkins stills agglutinin aosd aplastic autoimmune calcium classification cold deposition gout hemolytic hemophagocytic hlh
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Comparison ... - Pel-Ebstein fever ... body, but can also ... • Other hematologic ... #differential #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Coxsackie, CMV, EBV ... Prunelle Getten #AdultOnset ... diagnosis #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... Systemic AOSD: high fever ... , CRP, AST+ALT, ... BrighamChiefs #AdultOnset ... Disease #AOSD #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... • Dyspnea • Fever ... scans and can also ... Treatment • Early ... classification #hematology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... calcification appears as ... 12-24 Hours • Fever ... #Gout #Comparison ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Hodgkin, T-cell lymphoma ... , B-cell lymphoma ... Unknown cause Treatment ... #summary #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... to repair DNA, as ... aplastic anemia Treatment ... Anemia #oncology #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
calcification appears as ... Acute Pseudogout: Treatment ... it may present as ... acute neck pain, fever ... Deposition #Disease #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Monoclonal - Lymphoid ... - Mycoplasma, EBV ... Disorders Such As ... Symptoms: High fevers ... hemolytic #anemia #hematology
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