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diagnosis oncology disease syndrome algorithm differential hemophagocytic hlh hodgkins lymphohistiocytosis lymphoma stills : activation advancedcopd anemia aosd aplastic apml blvr
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Coxsackie, CMV, EBV ... Prunelle Getten #AdultOnset ... Disease #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
, CRP, AST+ALT, ... BrighamChiefs #AdultOnset ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome (ASS ... Body Myositis (IBM ... Idiopathic #Myopathy #Comparison ... #Managment #algorithm ... #Rheumatology #
Interventional bronchoscopic and surgical treatments for chronic obstructive pulmonary disease (COPD). Overview of various therapies used
bronchoscopic and surgical treatments ... patients with COPD ... long-term outcomes or comparison ... EBV: endobronchial ... #Management #AdvancedCOPD
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... calcification appears as ... 12-24 Hours • Fever ... #Gout #Comparison ... #rheumatology #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... - Pel-Ebstein fever ... body, but can also ... #NonHodgkins #comparison ... #differential #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... #diagnosis #management ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... to repair DNA, as ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
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