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diagnosis hematology management chronic cll lymphocytic algorithm aplastic cancer cell classification gammopathy hemeonc hodgkins lymphoma mds mgus monoclonal multiple myelodysplasia
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... disease 48% (light chain ... hypercalcemia) • Anemia ... ) Diagnosis - Clonal ... Diagnosis #Management #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
cytometry → >500/uL clonal ... immunophenotype Clinical ... of anemia or thrombocytopenia ... marrow failure with anemia ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... - infiltrates (anemia ... • Age: 60-80 Clonal ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... constitutional symptoms ... type) < 3 g/dL • Clonal ... insufficiency, Anemia ... hematology #diagnosis #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... virus (EBV) • Leukemia ... • Improve the symptoms ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... • Hairy Cell Leukemia ... Workup: • Complete ... diagnosis #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... classification #hematology #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
cytopenias, and clonal ... with a risk of clonal ... acute myeloid leukemia ... disease tolerate anemia ... importance of clinical
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... biopsy negative or clonal ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
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