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diagnosis management neurology hematology cll differential lymphocytic spinal spinalcord algorithm als amyotrophic behcet disease disorders hemeonc lesions ms multiple rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... • Age: 60-80 Clonal ... #Hematology #Oncology
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... injury - Multiple sclerosis ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... are spared Conus
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... cytometry → >500/uL clonal ... immunophenotype Clinical ... uw_IMresidency #CLL #Chronic ... #oncology #hematology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... Tract Lesions: • Bilateral ... : - Multiple sclerosis ... Scleroderma, Systemic sclerosis ... MCTD, Sjogren syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... with no early symptoms ... #CLL #Chronic ... diagnosis #workup #oncology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Hyperreflexia, Clonus ... patients with clinically ... stimulation Clinical ... Progressive MS (Spinal cord
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... cellular function Clinical ... multiple spinal cord ... Jaw Jerk reflex, Clonus ... fasciculations Common Symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... matter, spinal cord ... (Clinical Dx). ... tears, Ischemia, Leukemia ... Recurrent and chronic
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