9 results
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Abnormalities: Ocular Clonus ... Hyperreflexia, Muscle clonus ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Abnormalities: Ocular Clonus ... Hyperreflexia, Muscle clonus ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... cytometry → >500/uL clonal ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... hematology #hemeonc #diagnosis
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology
Imaging Findings:
 • Os trigonum which has marrow
Syndrome - MSK Radiology ... flexor hallucis longus ... Differential diagnosis ... flexion but no symptoms ... #diagnosis #msk
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... • Age: 60-80 Clonal ... Leukemia #Hematology #Oncology ... #Diagnosis
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... un lymphatic Diagnostic ... #management #cardiology ... #pharmacology #
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
constitutional symptoms ... type) < 3 g/dL • Clonal ... proliferative disorder • Clonal ... Significance #hematology #diagnosis ... #oncology
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Incidence, Symptoms ... SideEffects #Table #Diagnosis ... #Pharmacology # ... Oncology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
heart failure symptoms ... Cardiotoxicity #cardiology ... #oncology #pharmacology