9 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Psoriasis • Lichen Planus ... : • Lymphoma ... • Leukemia • ... Myelodisplastic syndrome
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... develop leukostasis syndrome ... • Tumor lysis syndrome ... • Age: 60-80 Clonal ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... with no early symptoms ... ’s CLL Scoring system ... Pure red cell aplasia ... diagnosis #workup #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
lymph nodes - Pruritus ... involved) • No leukemic ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... : • Lymphoma ... • Leukemia • ... Myelodisplastic syndrome ... #secondary #systemic
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... Episcleritis Signs and Symptoms ... development of skin symptoms ... (malignancy), lymphoma ... #dermatology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... meningitis), MCC CNS symptoms ... Behcet disease) Differential ... tears, Ischemia, Leukemia ... , Lymphoma Ocular
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Causes • Anemia • Aplastic ... • Hairy Cell Leukemia ... blood count with differential ... diagnosis #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Angioimmunoblastic T-cell lymphoma ... Induced Lupus: • Symptoms ... and leukemia