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diagnosis hematology algorithm chronic classification differential lymphoma management workup cancer cell comparison disorders erythematosus gammopathy hemeonc lupus lymphomas lymphoproliferative mds
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... • Age: 60-80 Clonal ... CLL Symptoms: • ... Leukemia (CLL) ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... with no early symptoms ... • Neutropenia, anemia ... leukemia #CLL ... #workup #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... cytometry → >500/uL clonal ... marrow failure with anemia ... uw_IMresidency #CLL ... #Leukemia #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- B symptoms ... involved) • No leukemic ... Nodal disease: B symptoms ... Diagnosis of B-Symptoms ... NonHodgkins #comparison #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... ingestion • B symptoms ... classification #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm Hodgkin ... Depletion Non-Hodgkin ... pattern of spread, B symptoms ... ~10% - B-Cell ... Treated Like Acute Leukemias
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... count (anemia) ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... diagnosis #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... constitutional symptoms ... insufficiency, Anemia ... to the plasma cell ... hematology #diagnosis #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... : • Chronic B-cell ... cyclophosphamide) • Hodgkin ... lymphoma and leukemia
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
cytopenias, and clonal ... with a risk of clonal ... acute myeloid leukemia ... disease-associated symptoms ... disease tolerate anemia
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