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diagnosis hematology management algorithm chronic classification cll aplastic cancer differential erythematosus gammopathy hemeonc hodgkins lupus lymphoma lymphomas lymphoproliferative mgus monoclonal
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
in adults • Disorder ... cytometry → >500/uL clonal ... marrow failure with anemia ... Lauren Banaszak, MD ... #Leukemia #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... - infiltrates (anemia ... Leukemia): • Lymphocytes ... • Age: 60-80 Clonal ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... with no early symptoms ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... - Amy Chung, MD ... Lymphoproliferative #Disorders
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
myelodysplastic syndrome (MDS ... virus (EBV) • Leukemia ... Hypocellular/Hypoplastic MDS ... • Improve the symptoms ... #oncology #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... constitutional symptoms ... insufficiency, Anemia ... • Clonal bone ... hematology #diagnosis #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... diagnosis #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... Immune hemolytic anemia ... ingestion • B symptoms ... classification #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) • Endocrine disorders ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... (C3 and C4) • ds-DNA ... Hodgkin lymphoma and leukemia
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
cytopenias, and clonal ... with a risk of clonal ... acute myeloid leukemia ... disease-associated symptoms ... disease tolerate anemia
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