33 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... on Smear • Chronic ... • Anemia of Chronic ... Spherocytes on Smear ... Non-lmmune #Anemia
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... and Howell Jolly ... Pathology #Hematology #Smear
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... • Extrinsic RBC ... • Intrinsic RBC
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
photo are a Howell-Jolly ... with hemolytic anemias ... #Clinical #Path ... BloodSmear #Blood #Smear
Red Blood Cell Morphology Atlas

Size variation, Hemoglobin distribution,  
Hypochromia,  
Shape variation,  
Inclusions, 
Red
#Diagnosis #Path ... #Blood #Smear # ... RBC #Morphology
Common RBC Inclusions and Associations
 • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia
 • Heinz
Common RBC Inclusions ... Associations • Howell Jolly ... Severe hemolytic anemia ... , Hemolytic anemia ... Sickle cell, MDS #RBC
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... #Clinical #Path ... BloodSmear #Blood #Smear
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
red blood cells (RBCs ... serum due to the RBCs ... #Clinical #Path ... #Blood #Smear #Microscopy ... #RBC #Autoagglutination
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
red blood cells (RBCs ... serum due to the RBCs ... #Clinical #Path ... #Blood #Smear #Microscopy ... #RBC #Autoagglutination
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... #Clinical #Path ... BloodSmear #Blood #Smear