13 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long bones ... • Differentiate ... SickleCell #Disease #differential ... #diagnosis #causes
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
Secondary Causes ... Some other random ones ... Priapism #Diagnosis #Management ... #Urology #Differential
Notice that there are multiple densities in both lungs.
The larger ones are ill-defined and maybe there
The larger ones ... are ill-defined ... masses. ... dealing with the differential ... Clinical #Radiology #CXR
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Chronic diarrhea / IBD ... Pancreatitis - Hungry bones ... Hypomagnesemia #Differential ... Classification #Causes
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... Diagnosis Algorithm ... Chemotherapy • Bone ... Celiac, IBD) • ... endocrinology #causes
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
Algorithm • 40- ... Receptor (sTfR) to differentiate ... /other causes • ... #Algorithm #diagnosis ... #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammation of the bones ... Rule out other causes ... -1 inhibitors, IL ... inhibitors, and IL ... Rheumatology #diagnosis #management
COVID-19 Chest Xray - First case of 2019 novel coronavirus in Canada
Chest x-ray shows bilateral, peribronchovascular,
Chest Xray - First case ... peribronchovascular, ill-defi ... opacities in all lung zones ... COVID19 #ChestXray #CXR
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill ... infiltration) Differential ... obgyn #diagnosis #management
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Phos), CBC with differential ... HFNC or BiPAP if mild-moderate ... to avoid (main ones ... MyastheniaGravis #Checklist #Management