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diagnosis differential hematology rheumatology bruising dermatology management nonpalpable palpable thrombocytopenia vasculitis algorithm amyloid amyloidosis anemia ascorbicacid atlas basics blanching bruise
Causes of Purpura - Differential Diagnosis Disruption in Vascular Integrity: • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... collagen vascular disorders ... , Nutritional deficiencies ... C), Pigmented purpuric ... nonpalpable #palpable #Causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
, vascular disorders ... , coagulation disorders ... , or other causes ... • Secondary Causes ... - Protein C/S deficiencies
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Sequestration Disordered ... Connective Tissue Disorders ... Disease • Other deficiencies ... Coagulation #Bleeding
Complications after Bariatric Surgery Post Bariatric Intestinal Failure: • Severe protein malnutrition after bariatric surgery • More
hyperglycemia and vitamin deficiencies ... inuslin release leading ... after RYGB • Disorder ... Gastric bypass causes ... prevention of hepatopathy
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... - History of bleeding ... epistaxis, gingival bleeding ... nutrient deficienies ... primary hematologic disorder
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
areas of the body Purpura ... Purpura due to vasculitis ... Wet purpura is the ... ecchymosis) is caused ... coagulation factor deficiencies
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Ketosis Disorders ... Treat other deficiencies ... ketoacidosis (DKA) - caused ... Glucosuria causes ... nickmmark #Ketosis #Disorders
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic purpura ... lymphoproliferative disorders ... Defects: Enzyme deficiencies ... Extravascular #Causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Arthralgia - Purpura ... Cryoglobulins Cause ... triad of Palpable purpura
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Disorders of ... of a platelet disorder ... deficiency • Disorders ... discern these causes ... Combined factor deficiencies
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