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differential syndrome hiv infectiousdiseases barre cns dementia encephalopathy guillain guillainbarre immune inflammatory ms multiple mycoses myelitis neurocognitive opportunistic polychondritis posterior
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
Disorder (HAND) ... Diagnosis: MRI ... syndrome of HAD ... is also associated ... #Neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
• IRIS might ... should be based on clinical ... Antimicrobial treatment ... Suspect in movement disorders ... InfectiousDiseases #Neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
of HIV/AIDS patients ... criteria, but the ... be present: • AIDS ... Other Pathogens Associated ... #Management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... Criteria: • Sensory ... /or symptoms • ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
fluctuations PRES-Associated ... dysfunction is key ... Neurological symptoms ... #diagnosis #management ... #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... response preceding infection ... #diagnosis #management ... #treatment #neurology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... impairment, Mood disorder ... Signs and symptoms ... criteria for MS ... #management #neurology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
by culture or serology ... yeast • At risk: AIDS ... Aspergillosis Pathophysiology ... : • Serology for ... #Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... fatigue Criteria ... Other organs Also ... ○ Syphilis ○ Fungal ... #management
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