8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Prednisone 5mg/kg ... fluid overload, PCC ... #diagnosis #management ... #hematology #oncology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
(both ALL and AML ... with Ca only if EKG ... Rasburicase (6mg) Key ... Syndrome #TLS #oncology ... #management #UricAcid
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
inflammation (eg ... been reported (eg ... Anti-LKM & Anti-ALC ... of Hepatitis (eg ... Histology Findings (eg
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... malignant syndrome (e.g ... #Management #Workup
Myocarditis 

5 Principles of
Myocarditis:
1. Build clinical suspicion
2. Decide on EMBx
3. Manage acute cardiac injury
4. Manage chronic
Pericarditis, Tamponade EKG ... Low voltage Treatment ... agent, steroids, AC ... #Myocarditis #diagnosis ... #management #cardiology
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
remember to tailor treatment ... obtain 12-lead ECG ... #Tachycardia #Anesthesiology ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... known drug causes (eg ... #Bradycardia #Anesthesiology ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Key Components: ... indicated • EKG ... Obtain EKG if: ... medical and surgical management ... stratification #diagnosis