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management hematology dermatology antinxp2 antinxp2dm calcium cancer comparison deposition dermatomyositis differential encephalopathy gout hemophagocytic hlh lymphohistiocytosis neuritis neurology ophthalmology optic
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
weird joints (shoulders ... • Underlying disease ... • Metabolic syndrome ... forefoot, ankles, knees ... Gout #Comparison #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
weird joints (shoulders ... Wrist, MCP or shoulder ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... #Rheumatology #
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Management Summary Diagnostic ... • Treatment algorithms ... aspirin • Aspirin should ... von Willebrand disease ... #hematology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... MRI: ON- focal, anterior ... Typical MS-like ON: should ... other auto-immune diseases ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... • Bicytopenia Treatment ... • Infection should ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... on MRA/CTA • Anterior ... count in the CSF should ... epilepticus Treatment ... underlying cause • Treatment
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
involvement: May involve anterior ... and lower jaw Treatment ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... algorithm 2018. ... median age at diagnosis ... #algorithm #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
the face, or the anterior ... , and back and shoulders ... had more severe disease ... positive patients Treatment ... #management #rheumatology
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