11 results
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... involvement: May involve anterior ... #Rheumatology # ... diagnosis #management ... #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... • Fever is the main ... #Diagnosis #Management ... #Hematology #Rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
of hands/feet, knees ... , shoulders Signs ... inflammatory) • joint pain ... Arthritis #diagnosis #management ... #rheumatology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Diagnosis and Management ... Moderate orbital pain ... MRI: ON- focal, anterior ... Typical MS-like ON: should ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... • Infection should ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... effusions, weight gain ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
weird joints (shoulders ... onset of swelling, pain ... • Metabolic syndrome ... forefoot, ankles, knees ... Gout #Comparison #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
supraclavicular node • Anterior ... hemolytic anemia • Pain ... classification #hematology ... #oncology #management
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... forefoot, ankles, knees ... swelling, significant pain ... #treatment #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
weird joints (shoulders ... onset of swelling, pain ... Crowned Dens Syndrome ... Deposition #Disease #Rheumatology ... #diagnosis #management