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disease stills syndrome adultonset activation adult cardiology differential fungal hematology immune infections infectiousdiseases inflammatory iris macrophage mas mycoses onset pericarditis
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
episode (30%) Systemic ... synovitis (40%) Treatment ... #rheumatology # ... diagnosis #management ... #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... solid cancers • Systemic ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Still's Disease Systemic ... Treatment - Mild ... Stills #disease #AOSD ... #diagnosis #rheumatology ... #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Usual interstitial pneumonia ... , INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
reconstituted immune system ... Lymphadenitis, pulmonary ... lymphadenitis, pulmonary ... cryptococcomas, cavitating pneumonia ... #Management
Acute Recurrent Pericarditis = recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
Myopericarditis, Systemic ... symptoms: pulmonary ... #Pericarditis #diagnosis ... #management #treatment ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... , systemic or meningitic ... the circulatory system ... Fluconazole SYSTEMIC ... #Management #Infections
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