31 results
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Diagnosis Framework ... Effusions: - Hematologic ... - Aneurysmal bone ... #diagnosis #msk
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... • Bone and joint ... as the collar bone ... and lower jaw Treatment ... #diagnosis #management
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
fragmentation and mild bone ... tibial tuberosity Differential ... marrow edema and bony ... Schlatter #Disease #Knee ... #msk
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
and Management ... Summary Clinical ... disease Imaging and Treatment ... Bone scan is indicated ... patients with bone
Focal Periphyseal Edema (FOPE lesion) - MSK Radiology
Imaging Findings:
 • Arrows identifying the characteristic edema-like signal
FOPE lesion) - MSK ... atraumatic adolescent knee ... physeal fusion and bone ... (save $$) Differential ... • Bone contusion
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Liver function tests ... hemophagocytosis in the bone ... CD163 staining of bone ... is found in the bone ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... , Biological + Bone ... Assessment • Clinical ... /ml, ↑ LDH • Bone ... #management #treatment
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Ligament • Bone ... the subchondral bone ... #Joint #Pain #MSK ... approach #workup #differential ... #diagnosis #arthritis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... Hypoplastic MDS: • ↓ bone ... • Suggested by bone ... hypoplasia/fatty bone ... #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... myasthenia Diagnosis ... Bedside: ice pack test ... /Edrophonium test ... #management #neurology