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Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
vs Korsakoff Syndrome ... - Thiamine Deficiency ... is Korsakoff's ... #Korsakoff #Syndrome ... #diagnosis #comparison
Korsakoff Syndrome
Clinical Findings:
 • Confabulation: Usually initial phase of the disease
 • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... presentation of Thiamine ... untreated Wernicke Encephalopathy ... factors of Wernicke Encephalopathy ... #diagnosis
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Wernicke Encephalopathy ... ) Deficiency - Diagnosis ... and Management Diagnosis ... development of Korsakoff ... syndrome (chronic
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Differential Diagnosis ... hyperventilation Wernicke-Korsakoff ... Encephalopathy ... consistent with WKS • Korsakoff ... #Differential #Diagnosis
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Water-Soluble Vitamins: • Thiamine ... (encephalopathy ... gait ataxia), Korsakoff ... syndrome (amnesia ... #differential #diagnosis
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Wernicke Encephalopathy ... - Acute Thiamine ... Deficiency Clinical Diagnosis ... #Thiamine #B1 # ... Deficiency #diagnosis
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Vitamins: • Thiamine ... Beri-beri, Wernicke-Korsakoff ... syndrome • Riboflavin ... #differential #diagnosis
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Metabolism -> Decr Thiamine ... - Wernicke-Korsakoff ... Syndrome - ... #diagnosis #pathophysiology
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Varices • Hepatic Encephalopathy ... Hepatopulmonary Syndrome ... • Hepatorenal Syndrom ... Complications #diagnosis
AEIOU TIPS - Mnemonic for Causes of Altered Mental Status
A - Alcohol, Acidosis, Ammonia, Arrhythmia
E -
Temperature, Trauma, Thiamine ... MentalStatus #AMS #encephalopathy ... #diagnosis #differential