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differential hematology algorithm treatment gastroenterology ascites cholangitis complications encephalopathy hepatopulmonary injury neurology oncology primary renal rheumatology summary thrombocytopenia workup abnormal
End Stage Liver Disease (Cirrhosis) - Complications • Ascites • Esophageal Varices • Hepatic
Disease (Cirrhosis ... Hepatopulmonary Syndrome ... • Hepatorenal Syndrom ... #diagnosis #management ... #summary #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Nonalcoholic fatty liver ... disease (Budd-Chiari syndrome ... 14 percent) #Diagnosis ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... and hepatorenal syndrome ... Clues to non-cirrhotic ... sarcoidosis) • Liver ... #causes #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Algorithm #Causes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... or symptoms of ... #differential #Diagnosis ... gastroenterology #hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction 1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... , Polycystic liver ... post-sinusoidal: Budd-Chiari syndrome ... #differential #diagnosis ... #causes #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... • Budd-Chiari Syndrome ... Primary Biliary Cirrhosis ... #Algorithm #Causes ... #Hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... - Hepatic: • Cirrhosis ... disease • Acute liver ... #Algorithm #Hepatology ... #causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... #Pregnancy #hepatology ... #management #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... /Liver failure ... PBC Signs and Symptoms ... #workup #hepatology
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