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management neurology rheumatology disease agglutinin algorithm als amyotrophic anemia arteritis autoimmune behcet cns cold disorders encephalitis gca giantcell hemolytic infections
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... - Mycoplasma, EBV ... younger pts) Differential ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential ... Diagnosis Framework ... neurological lesion: Clinical ... and signs below ... #neurology #differential
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... multiple spinal cord ... fasciculations Common Symptoms ... EMG: LMN Signs in ... conditions listed in differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... matter, spinal cord ... Behcet disease) Differential ... #management #signs ... #symptoms #rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... and/or symptoms ... Brucellosis - Dengue, EBV ... management #neurology #differential
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework Viral Encephalitis: MCC: Enteroviruses (e.g., coxsackievirus
virus • CMV • EBV ... Coltivirus Symptoms ... • Common clinical ... influenzae Symptoms ... Acute meningeal signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... very remarkable w/differential ... in literature (NEJM ... #Symptoms #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... papules and Gottron sign ... ) • Shawl sign ... • ANA < 20 % IBM ... #differential #
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