44 results
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... (e.g. heparin, LMWH ... weight heparin (LMWH ... #UFH #DOAC #Dabigatran ... #Fondaparinux #NOAC
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Kcentra) - Heparin/LMWH ... anticoagulation #doac ... #noac #pharmacology
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
anticoagulants (DOACs ... ) for VTE treatment ... Comparison Table #DOAC ... Anticoagulation #VTE
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Fibrillation, VTE ... Prophylaxis, VTE ... @Bloodman #DOAC ... Dabigatran #Edoxaban #NOAC
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC ... h) #Warfarin #DOAC ... #Pharmacology #NOAC
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
anticoagulants (DOACs ... filtration rate; DOAC ... anticoagulant; LMWH ... body mass index; VTE ... #DOAC #VTE #Malignancy
Best practice recommendations for the diagnosis and treatment of adult patients experiencing traumatic brain injury during
Brain #Injury #NOAC ... #DOAC #Management
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE ... initiated after a LMWH ... ¥LMWH is currently ... DOAC, direct oral ... #DOAC #VTE #Malignancy
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism