12 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... • Calcineurin Inhibitors ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... Medications ... #Medications #pharmacology ... #pathophysiology ... #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... #Renal #Dosing ... #Pharmacology #Management ... #Diabetes #DM2 ... #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Type 2 Inpatient Medication ... Sulfonylurea, TZD, DPP-4 inhibitor ... α-glucosidase inhibitor ... #pharmacology # ... comparison #table #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... medications, with ... #Pharmacology # ... Medications #DM2 ... #Diabetes #Endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... (EuDKA) SGLT2 Inhibitors ... Increasing Indications ... level < 200 mg/dL Pathophysiology ... diagnosis #management #endocrinology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Correction of diabetic ... osmotic diuresis - Potassium ... - Proton pump inhibitors ... #differential #medications ... #drugs #pharmacology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
) MECHANISM: Potassium ... oral suspension DOSING ... with CKD, HF, or diabetes ... ACE inhibitors, ... #Hyperkalemia #Pharmacology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
commonly used medications ... to treat Type 2 Diabetes ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Clenching of fist during ... NSAIDs • ACE Inhibitors ... • Recent IV potassium ... (Uncontrolled diabetes ... Medications 2.