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diagnosis management polycythemiavera treatment differential et pv thrombosis vascular acutelimbischemia ali arterial attack cli clinical comparison criteria defects embolectomy embolism
Polycythemia vera, Essential thrombocythemia, Primary myelofibrosis Diagnosis Algorithm • Polycythemia vera → Blood JAK2 mutation screening
vera → Blood JAK2 mutation ... thrombocythemia → Blood mutation ... marrow biopsy with mutation ... cytogenetics #hematology
Limb-Shaking Transient Ischemic Attack (LS-TIA) Limb shaking Transient Ischemic Attack (LS-TIA) during transient occlusion of the right
right ICA during angioplasty ... Ischemic #Attack #LSTIA ... intraoperative #vascular #angioplasty
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 Acute limb ischemia (ALI) Rapid decrease in lower limb blood flow due to acute occlusion of peripheral
of guide wires, angioplasty ... #CLI #heparin #amputation
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Factor V Leiden mutation ... Prothrombin gene mutation ... pathophysiology #hematology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC mutation ... Indications #management #hepatology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
mobility due to mutation ... differential #diagnosis #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
growth AND • JAK2 mutation ... Summary #treatment #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
have a specific mutation ... Syndromes #diagnosis #hematology
Polycythemia Vera • A clonal proliferation of myeloid cells • Increased RBC mass, JAK2 mutation •
RBC mass, JAK2 mutation ... WHO #Criteria #Hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
ET-associated mutation ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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