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diagnosis management symptoms neurology clinical treatment abnormal cardiology differential psychiatry abnormalities algorithm atlas barre beaus breathing bulimianervosa chf comatose complications
Characteristic clinical manifestations of Down syndrome Typical craniofacial appearance • Round face and flat
• Brushfield spots ... iris (pigmented spots ... #Downs #Syndrome ... #PhysicalExam # ... Features #Signs
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... fractures • Short ... #genetics #pathophysiology
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... by: - drugs (e.g ... Pathophysiology: ... FatimahDandan #Pisa #Syndrome ... pleurothotonus #PhysicalExam
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 Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... unless worrisome EKG
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... deficiency: - Short ... tissue expansion (e.g ... endocrinology #pathophysiology
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... Low BMI < 18.5 kg ... #diagnosis #pathophysiology ... #symptoms #signs
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... • Lhermitte’s sign ... Signs and symptoms ... VEP’s: EEG of visual ... taper 3-7 days - Short
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... Miller Fisher Syndrome ... Electrodiagnostic studies - EMG
Causes of ST Segment Elevation - Differential Diagnosis Framework STEMI: • Upsloping convex STE: "Pardee's sign" +
STE: "Pardee's sign ... interval J Wave Syndromes ... involved • Brugada Syndrome ... (Eiffel Tower sign ... #ekg #electrocardiogram
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... of diagnosis (e.g ... Specific sarcoidosis syndromes ... • Heerfordt syndrome ... Diagnosis #Management #Signs
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