23 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... • Weakness: Starts ... Treatment: • Plasmapheresis ... #management #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... unless worrisome EKG ... TLS #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... and cauda equina TREATMENT ... #Syndrome #diagnosis ... #management #neurology
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... Hyperkalemia Typical ECG ... • Aggressive treatment ... #diagnosis #management ... #pathophysiology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Treatment ... taper 3-7 days - Short ... sclerosis #diagnosis #management ... #neurology #treatment
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... Serologic and EMG ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... hyperthermia crisis (late sign ... • Serotonin syndrome ... Anticholinergic syndrome ... Checklist #Diagnosis #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... cerebritis #diagnosis #management ... #treatment
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... Treatment: • ... SPS #Diagnosis #Management ... #treatment #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
myopathy, Guillain-Barré ... syndrome (GBS), ... (SAMS-CI) • EMG ... myopathy #diagnosis #management ... #treatment