10 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... Differential Diagnosis ... Malignancy (e.g. hematologic ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... Labs/Diagnosis: ... systemic lupus erythematosus ... #types #classification ... #rheumatology #
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
- Differential Diagnosis ... Capitis - Skin ... Discoid lupus erythematosus ... , Loose anagen syndrome ... Examine the entire skin
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... #diagnosis #dermatology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... : erythematous nodules ... systemic lupus erythematosus ... #rheumatology # ... classification
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... lymphoproliferative disorders ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... just beneath the skin ... Neutropenia • Platelet Disorders ... #diagnosis #hematology ... #oncology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
membrane bleeding and skin ... Marfan syndrome, ... #History #peds ... #pediatrics #diagnosis ... #hematology #primarycare
Pathergy Summary Overview

What is pathergy?
Pathergy is an exaggerated skin injury occurring after minor trauma such as
Skin trauma → Erythematous ... (PG) • Sweet syndrome ... Myeloproliferative disorders ... • Blind loop syndrome ... #Pathergy #diagnosis