19 results
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology
Risk factors:
 - Low CD4 count
 - Disseminated OI
 -
Immune Reconstitution ... (IRIS) - Pathophysiology ... factors: - Low CD4 ... Syndrome #IRIS #Pathophysiology ... #AIDS
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
CD3-CD4+ T cells ... HTLVI) - Chronic inflammatory ... related disease, inflammatory ... malignancy - Immune ... hypereosinophilia #HE #Differential
Important causes of diarrhea in people with HIV/AIDS
Severity, chronicity/persistence will depend On CD4 count & sites
people with HIV/AIDS ... will depend On CD4 ... Kaposrs sarcoma, AIDS ... #Diarrhea #HIVAIDS ... #Differential #
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Infections in HIV-AIDS ... ) Fungal: • CD4 ... Pulmonary #Infections #HIVAIDS ... diagnosis #evaluation #differential ... #CD4
Blurry vision in a patient with HIV/AIDS
Anterior Segment:
 • Herpes zoster ophthalmicus
 • Keratitis (HSV, Staph,
patient with HIV/AIDS ... seen with lower CD4 ... Blurry #vision #HIVAIDS ... Anterior #Posterior #Differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... Leishmaniasis Differential ... #Syndrome #Differential
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... - Differential ... required until immune ... CNS #Infections #differential ... #diagnosis #AIDS
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... production of pro-inflammatory ... Others: Cellular immune
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... abnormalities • Inflammatory ... #Bandemia #differential ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Necrotizing, pauci-immune ... respiratory tracts Immune ... Syndrome: - Ocular inflammatory ... Lab Tests: • CBC