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management differential infectiousdiseases syndrome hiv activetb barre guillain hemophagocytic hivaids hlh latenttb lung lymphohistiocytosis opportunistic tb tuberculosis abscess aspergillus associated
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... in HIV-AIDS Bacterial ... < 200: Pulmonary ... ID_fellows #Pulmonary ... #workup #diagnosis
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
impaired cellular immune ... , Advanced HIV/AIDS ... presentations: • Pulmonary ... #Management #treatment ... #fungal #infectiousdiseases
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
CMV infection: virus ... Diagnosis: Quantitative ... patient with HIV and CD4 ... 50 or less: • Neurologic ... Pancreatitis • Pulmonary
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... Antimicrobial treatment ... required until immune ... #AIDS #opportunistic
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
: • Direct fungal ... by culture or serology ... yeast • At risk: AIDS ... Aspergillosis Pathophysiology ... : • Serology for
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Syndromes: • Pauci-Immune ... allopurinol), Infection ... DAH, rule out infection ... #nephrology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... that disrupts immune ... Others: Cellular immune ... #management #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Immune Reconstitution ... of HIV/AIDS patients ... be present: • AIDS ... Lymphadenitis, pulmonary ... lymphadenitis, pulmonary
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... (NTM) • Fungal ... Progression: (+) Immune ... rest LTBI (-) Immune ... Tuberculosis Diagnosis
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... (NTM) • Fungal ... Progression: (+) Immune ... rest LTBI (-) Immune ... Tuberculosis Diagnosis
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