601 results
Inherited Colorectal Cancer (CRS) Syndromes
Adenomatous Polyposis Syndromes:
 • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Colorectal Cancer (CRS) Syndromes ... : • "CRC + Endometrial ... Urinary → Lynch Syndrome ... Cronkhite-Canada (CC ... #diagnosis #management
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... glomerulonephritis - Berger disease ... Minimal change disease ... #Glomerular #Diseases ... Classification #Nephrology #Diagnosis
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
of autoimmune disease ... , CD3, CD8 - Loss ... of CD5 and/or CD7 ... morphologic/clinical disease ... hemepath #pathology #diagnosis
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Multi-System Inflammatory Syndrome ... Kawasaki Disease ... CDC Case Definition ... other reasons for disease ... Kawasaki #Comparison #diagnosis
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
reaction - Atopic disease ... lymphomas, Hodgkin disease ... CD3-CD4+ T cells ... , IgG4-related disease ... #Differential #Diagnosis
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Castleman's Disease ... and Associated Syndromes ... with Castleman's disease ... Pathogenesis "IL6 syndrome ... #Variants #Diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
and less common diseases ... important, as early diagnosis ... Vogt-Koyanagi-Harada (VKH) disease ... polychondritis • Behcet disease ... #differential #diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Differential Diagnosis ... Pulmonary Renal Syndromes ... Investigations • Labs: CBC ... #differential #diagnosis
Chronic Diarrhea - Differential Diagnosis Algorithm
Steatorrhea
 - Maldigestive
    • Pancreatic Insufficiency
 - Primary
- Differential Diagnosis ... Irritable Bowel Syndrome ... Irritable Bowel Syndrome ... (diagnosis of exclusion ... (Screen with CBC
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
Churg-Strauss syndrome ... - Schnitzler syndrome ... - Sjögren syndrome ... Vasculitis #Vessels #Diagnosis ... #Rheumatology #Diagnosis