11 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Proximal tubule Bartter ... Syndrome #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Algorithm Extra-renal ... loss (Diarrhea) Renal ... thiazide diuretics, Bartter ... potassium #low #nephrology
Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Differential Diagnosis Renal ... Hypomagnesemia - Familial: Bartter ... with secondary, hypocalcemia ... hypomagnesemia Renal ... diagnosis #causes #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... gastrointestinal K loss • Renal ... • Renal tubular ... • Diuretics, Bartter's ... algorithm #causes #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... suggests extra-renal ... Emesis, Diuretics, Bartter ... differential #potassium #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Villous adenoma Renal ... chewing tobacco, Renal ... Osmotic diuresis, Bartter's ... differential #diagnosis #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
(renal potassium ... Sjögren syndrome, Renal ... Refeeding syndrome • Bartter ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Diarrhea • RENAL ... - Diuresis - Bartter ... gas transport, renal ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... paralysis/familial hypokalemic ... Loop diuretics / Bartter's ... aldosterone • Renal ... #Nephrology #Differential
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
To prevent hypokalemia ... patient has good renal ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology