11 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Antitrypsin • Other: NAFLD ... Malignancy, 1° PBC ... Differential #Diagnosis #Causes ... Acute #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Neutrophils - Low RBC ... • Pancreatic Disease ... Disease #Macrocytic ... #Hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... diagnosis #workup #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
: INR/PT, aPTT(liver ... disease, decrease ... changes), high MCV anemia ... disease), HBsAg ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... Disease: - Impaired ... Treat primary cause ... Coagulation #diagnosis #causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Malnutrition • Wilson's disease ... • Pernicious anemia ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
- Pathophysiology ... prolonged rest can cause ... deficiencies • Renal, liver ... of renal disease ... #pathophysiology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
• Heavy chain disease ... Sarcoidosis) • Liver ... disease: Cirrhosis ... autoimmune hepatitis, PBC ... Thalassemia, Sickle cell anemia
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
disease characterized ... abnormalities PATHOPHYSIOLOGY ... overperfusion + decreased RBC ... arteriovenous shunting causes ... cirrhosis #diagnosis #hepatology