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diagnosis rheumatology classification management agglutinin ana antinuclear apml cold differentiation disease erythematosus hemolytic hodgkins hyperpnea infectiousdiseases lupus lymphoma mycobacteria nontuberculous
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... younger pts) Differential ... chills, flank pain ... #hematology #diagnosis
Tachypnea - Differential Diagnosis Framework Definitions • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults •
Tachypnea - Differential ... effusion/Tamponade Hematologic ... Tachypnea: • Anemia ... dysfunction; toxic ingestions ... Anxiety, fright, pain
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... diagnosis #management #hematology ... #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... Hematologic malignancy ... diarrhea, abdominal pain ... Bone Marrow - Anemia ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... to exclude are infections ... , testes -> pain ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Pain in LN ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... Arthritis: • Joint pain ... lymphopenia, low PLT • Anemia
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