10 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... VTE and bleeding complications ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology # ... rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
microglobulin Treatment ... kinase (BTK) Complications ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... workup #oncology #hematology
Complications after Bariatric Surgery
Post Bariatric Intestinal Failure:
 • Severe protein malnutrition after bariatric surgery
 • More
Complications after ... Consider refeeding syndrome ... nutrients • TPN for treatment ... deficiencies) Dumping Syndrome ... excluded limb • Treatment
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS
Previous Thrombosis?
Previous Pregnancy Complications?

Dr. Laurent ARNAUD @Lupusreference

#obstetrics
Antiphospholipid Syndrome ... Previous Pregnancy Complications ... Antiphospholipid #Syndrome ... EULAR2019 #guidelines #rheumatology ... #obgyn #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... #Rheumatology #
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
• MAGIC syndrome ... • Vexus syndrome ... Multiple myeloma Complications ... affected tissue Treatment ... Polychondritis #rheumatology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... of death from complications ... #algorithm #hematology