14 results
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... arthralgia, arm/leg ... Abdominal pain • HTN ... occasional oligoclonal bands ... purpura (lower legs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Clinical Findings ... cell-mediated immune ... Renal (10-50%) - HTN ... nephrotic/nephritic syndrome ... arthritis (especially knees
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology: • Immune ... Guillain-Barre Clinical ... Weakness: Starts in legs ... Reflexes: Arms or legs ... #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... ulceration • Ocular ... (Clinical Dx). ... Behcet disease) Differential ... #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Ocular- 50%: Ptosis ... weakness, arms > legs ... life-threatening Differential ... Gravis #diagnosis #management
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Differential Diagnosis ... 109 mm Hg) with clinical ... most pts have HTN ... White-coat syndrome ... Workup #causes #Differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... Reversible course Differential ... • EEG: With persistent ... • Treatment of HTN ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Management Summary ... activity → local immune ... renal failure Clinical ... extensor surface of legs ... Sarcoidosis #Diagnosis #Management
Ober's Test for TFL/ITB Inflammation

With the patient in the lateral position, affected side up.  The
slowly lowers the leg ... Test #Iliotibial #Band ... #Syndrome #ITBand ... #clinical #video ... #physicalexam #
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Inflammatory Syndrome ... skin lesions, ocular ... Zoster flare, ocular ... #Differential # ... Diagnosis #Management