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diagnosis hematology neurology differential hemophagocytic hlh lymphohistiocytosis symptoms vasculitis arthritis behcet comatose disease gravis hemeonc henochscholeinpurpura hsp iga macrophage mas
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Clinical Presentation ... Fever is the main clinical ... #Management #Hematology ... #Rheumatology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
Clinical Findings ... tissue site - Activation ... nephrotic/nephritic syndrome ... arthritis (especially knees ... Pathophysiology #Diagnosis #Signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
of hands/feet, knees ... , shoulders Signs ... Ultrasound Diagnosis: CLINICAL ... Arthritis #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... excessive macrophage activation ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... weakness, arms > legs ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... arthralgia, arm/leg ... Abdominal pain • HTN ... purpura (lower legs ... Differential #Diagnosis #Rheumatology
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
• Locked-in syndrome ... ascending reticular activating ... • Vestibulo-ocular ... • Examine for signs ... caseyalbin #PhysicalExam
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Transverse Myelitis - Clinical ... flexors of the legs ... • Bilateral signs ... Myelitis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
management. ... Syndrome) 3. ... Clinical Presentation ... • Common Signs ... #Hematology #HemeOnc
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