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management hematology oncology radiology rheumatology lymphoma differential neurology syndrome workup acquired aids anemia antinxp2 antinxp2dm aorta aortic aplastic biopsy cap
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... cells and Reed-Sternberg ... cells. ... Lymphoma - Clinical ... Lymphoma Treatment
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... underarms, or chest ... cells, natural ... killer (NK) cells ... Differential Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can infiltrate ... smear: Smudge cells ... or basket cells ... microglobulin Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Phagocytosis of blood cells ... Hemopathies+++: Hodgkin ... Drugs, Unknown cause ... Treatment: •
The CT-image is not very helpful in the differentiation. There are hypodense areas, which could be masses. On
The CT-image is ... which could be masses ... Finally the diagnosis ... #Clinical #Radiology ... #CXR #CTChest #
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
effects of SCC or Hodgkin ... Clinical Picture ... myasthenia Diagnosis ... Imaging - CT Chest ... Myasthenia #Gravis #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... cellularity + dysplastic cells ... number of CD34+ cells ... Number of CD34+ cells
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
aggregate foci (>50 cells ... aggregate) of CD4 T cells ... , B cells, and plasma ... cells around salivary ... ducts Clinical
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... Schistocytes, helmet cells ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
less than 200 cells ... should be based on clinical ... Antimicrobial treatment ... more than 200 cells ... enhancement on CT
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