90 results
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
causes development ... Particular CD4+ Th cells ... harmful -> Th Cells ... macrophages, mast cells ... #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... plasma cells that ... complexes bind to mast cells ... • Inflammatory cells ... #Immunology #pathophysiology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Immunological Mediator: Th Cells ... #Allergic #Reactions ... #Types #Classification
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Angioedema: • Acute allergic ... exposure • Non-allergic ... cell-mediated in > 90% of cases ... #Angioedema #Classification
Uveitis - Definition, Causes and SUN Classification

Inflammation of the iris, ciliary body, vitreous, retina and/or choroid
Incidence
- Definition, Causes ... and SUN Classification ... Bartonella SUN Classification ... #SUN #Classification ... Differential #Diagnosis #Ophthalmology
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
Bell's Palsy Bell ... an identifiable cause ... Bell’s palsy happens ... The cause is unknown ... neurology #anatomy #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... infection - Allergic ... disease Rare causes ... CD3-CD4+ T cells ... ) - Allergic bronchopulmonary
Allergic Rhinitis: Pathogenesis and clinical findings

1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... -> Helper T cells ... Tissue edema #Allergic ... Rhinitis #Rhinorrhea #pathophysiology
Asthma: immunopathogenesis. 
Allergens attach to, and are taken up by, dendritic cells that he the respiratory
by, dendritic cells ... interaction of the allergen ... T-helper (TH2) cells ... mucus production allergic ... immunopathogenesis #Pathophysiology