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diagnosis management tumor hematology acutekidneyinjury allergy cairoandbishop cancer differential emergencies etiology howardcriteria hyperkalemia hyperphosphatemia hypersensitivityreaction hyperuricemia hypocalcemia immunology leukemia leukostasis
Tumor Lysis Syndrome (TLS) Pathophysiology Culprits: ALL, Burkitt, SCLC Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... Burkitt, SCLC Cells ... #Syndrome #TLS ... #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: • Pathophysiology ... high WBC count cause ... Syndrome: • Pathophysiology ... cells releasing ... #Syndrome #TLS
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... of neoplastic cells ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... Walid Malki, MD, MS ... wandering_er #Tumor #Lysis ... #Syndrome #TLS ... #oncology #management
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Hyperviscosity Syndrome ... neutrophil count < 500 cells ... Superior Vena Cava Syndrome ... EMERGENCIES: Tumor Lysis ... Syndrome: • Azotemia
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
exposure to allergen causes ... harmful -> Th Cells ... or CTLs -> Inflammation ... Stevens-Johnson Syndrome ... Allergy #Immunology #pathophysiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... symptoms are not caused ... anterior/posterior MSK ... • Heerfordt syndrome
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... & DIC • Tumor lysis ... syndrome: Develops ... Leukemia #Hematology #Oncology
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